He actually turned this as an upside, saying during the show something like `I do a show about random things developers might also be interested in, not about developing` (I paraphrase heavily).
Perhaps they should rename the show.
For technical matters, the Hypecritical podcast is way way better.
The "might" there is the thing. I _might_ be interested in his home renovation, his personal preferences in regards to coffee, music and leasing cars or the fact that he's having a kid. I might, _if_ he were my brother-in-law.
From the the Instapaper guy, all I want to know is what he thinks about web/iOS development and running his own business. I get the impression lately that Marco is either out of material on development topics, or just not interested in discussing them.
EDIT:
That said, here's hoping Marco blasts out some awesome changes and makes Instapaper even better, love him or hate him he's an inspiration to one-man shops, and produces some great stuff.
For technical matters, the Hypecritical podcast is way way better.