NixOS. Takes the fear away due to atomic upgrades and rollbacks. Lot of people can't get pass this language nix though. GuixSd is an alternative to check out. There are other immutable distros too if you're looking for something less radical.
NixOS's automatic snapshots and atomic updates take the fear out of nearly everything in my computer. It's so much less scary for me to muck with boot parameters or kernel modules if I know that I can always reboot and choose a previous generation.
I've told this story here before, but a few months ago I bought a laptop and installed NixOS on there. It worked fine except my USB keyboard would take about 5 seconds to "wake up" if I stopped typing for more than a minute.
If this were any other distro, I probably would have just lived with it, because I would be afraid of breaking Grub to a point where I don't know how to fix it, but with NixOS I figured out how to fix it, and now it's fixed, and it's backed up with git so I always have it if I ever need to do this on another computer.
Seconding this; I used solely Ubuntu for 15 years but switched to NixOS a few years ago. Using an immutable system feels like a weight being lifted off my back.
